The Division of Pediatric Critical Care Medicine at Oishei Children's Hospital is an active participant in several multicenter trials seeking to expand the understanding of various aspects of critical illness in the pediatric population. It is one of approximately thirty centers involved in the HALF-PINT and CAF-PINT studies, examining the effects of insulin therapy for hyperglycemia on children with cardiac or respiratory failure, and the implications on coagulation and fibrinolysis in these patients, respectively. The division is also collaborating with members of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network to collect airway management data for the NEAR4KIDS registry, a multicenter, prospective registry for advanced airway management in pediatric intensive care units around the country.
Our division also supports self-sufficient, single-center work from its practicing physicians. For example, we are currently analyzing our unique experience with a novel form of non-invasive support for respiratory failure, the RTXTM ventilator, or chest cuirass, through both retrospective and prospective studies. In addition, our fellows attempt to answer a wide range of clinical questions, from the efficacy of non-invasive detection of acute kidney injury to the optimal route of nutrition delivery in critical illness to the practical implications of utilizing another novel mode of respiratory support, NAVA (neutrally-adjusted ventilator assistance) in respiratory failure. The division has another dozen studies in the design and proposal stages, with subject matter spanning from fluid overload to patient safety and inter-provider communication.